金纳米颗粒 可能很快就会变成 前列腺癌 治疗选择。显然，与常规 癌症 treatments such as uncontrolled bleeding, fatal blood clots 和 dangerous reactions to the anaesthetic, among others. To relieve patients from such risks, a new clinical trial in the US has utilized the Aurolase Nanoshell therapy to treat 前列腺癌 patients with minimal collateral damage to the surrounding tissues. Already eleven patients have undergone the procedure with promising results.
娜奥米·哈拉斯（Naomi Halas）, a senior researcher from the Rice University in the US, invented Auroshells (or 纳米壳) 和 collaborated with Jennifer West, a senior researcher in the 杜克大学 in the US, for applying the technology for treating 癌症. Both of the researchers co-founded the company–纳米光谱生物科学—制造用于癌症治疗领域的纳米壳。
In the new treatment methodology, MRI/ultrasound-guided ablation of gold nanoshell-loaded neoplastic lesions are done. The 纳米壳, composed of silica spheres with a gold shell, are delivered intravenously 和 subsequently, these accumulate in a tumour. 核磁共振和超声 are used to locate the 癌症ous lesions as accurately as possible. Then a fibre probe that emits infrared light is inserted into the lesion. The 纳米粒子 absorb the light, converting it into heat that destroys a tumour while sparing adjacent tissue.
In the clinical trials conducted so far, minimal side effects have resulted 和 there was no sign of relapse after three months following the procedure. Out of the eleven 前列腺癌 patients who underwent the procedure only two had shown adverse effects, which were, however, non-serious 和 self-resolving. The patients had prostate 癌症 lesions ranging between 0.23 和 3.28立方厘米 在体积上，平均患者的病变的格里森评分为
肿瘤消融后使用 Aurolase纳米壳, lesions of all patients undergoing the procedure were completely removed, proving that the therapy is safe 和 could be considered as a feasible treatment alternative to radiation 和 removal surgery.